4 edition of Physiological aspects of anaesthetics and inert gases found in the catalog.
Includes bibliographies and index.
|Statement||A. G. Macdonald and K. T. Wann.|
|Contributions||Wann, K. T. joint author.|
|LC Classifications||RD82 .M3|
|The Physical Object|
|Pagination||xii, 308 p. :|
|Number of Pages||308|
|LC Control Number||77081385|
The changes in volume and composition within the pocket were examined for a variety of inspired gas mixtures during anesthesia. Each gas mixture consisted of O 2 and a single inert gas, either N 2 or N 2 O. A range of F I O 2 from to was modeled, both with and without preoxygenation for 3 min. The effects of including or not including. Oganesson: A Most Unusual ‘Inert Gas’ and RIKEN (the Institute for Physical and Chemical Research). His research work has mainly been divided between experimental studies using the muon spin rotation method on materials ranging from fullerenes to semiconductors, and the application of computational chemistry to a variety of systems.
Preoxygenation increased the rate of gas uptake from the unventilated area of lung and was the most important determinant of the time to collapse. Increasing the inspired O 2 fraction during anesthesia reduced the time to collapse. Which inert gas (N 2 or N 2 O) was breathed during anesthesia had minimal effect on the time to collapse. Introduction. Gases with proven or exploratory medical use include oxygen, hydrogen, carbon monoxide, carbon dioxide, hydrogen sulfide, nitric oxide, nitrous oxide, xenon, argon, helium and other noble gases [1–4].In general, the relatively fast wash-in and wash-out of gases, and their application only for acute treatment (with the exception of oxygen), has made pharmacokinetic (PK) analysis.
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Physiological Aspects of Anaesthetics and Inert Gases You will receive an email whenever this article is corrected, updated, or cited in the literature. You can. Physiological aspects of anaesthetics and inert gases. London ; New York: Academic Press, (OCoLC) Document Type: Book: All Authors / Contributors: A G Macdonald; K T Wann.
Author(s): Macdonald,A G(Alister Gordon); Wann,Kenneth T Title(s): Physiological aspects of anaesthetics and inert gases/ A.
Macdonald and K. Wann. The most frequently used inert gases are those that are administered in anesthesia, and the specific issues relating to the uptake, transport, and elimination of these gases and vapors are dealt with in some detail showing how their transfer depends on various physical and chemical attributes, particularly their solubilities in blood and different by: 3.
In Physiological Aspects of Anaesthetics and Inert Gases (Edited by Macdonald A. and Wann K. T.), pp. Cited by: THE physicochemical aspects of the action of anaesthetics have been studied for many years, with general agreement on the following conclusions.
No chemical reaction seems to take place as in the. Some physiological aspects of five fish anaesthetics in rainbow trout were investigated.
The effects of benzocaine, 2-phenoxyethanol, MS (Sandoz), metomidate, and carbon dioxide gas (CO 2) on acid–base regulation, hematocrit, blood gases, and cortisol and adrenaline concentrations were determined in resting rainbow trout fitted with chronic catheters in the dorsal aorta.
Physical characteristics of some volatile anesthetic agents. particularly in the reticular activating system (see CNS & Anesthesia lecture) Practical aspects of the use of inhalational (volatile) anesthetic agents (inhalant anesthetics are considered to behave in the body as inert gases).
An inert gas is a gas that has extremely low reactivity with other substances. The noble gases—helium, argon, neon, xenon, krypton, radon, and element (Uuo)—exist in their elemental form. physiological problems of flight, and will instruct you in the use of some of the devices Gas is inert in the body and is simply stored in tissues and cells.
Oxygen (O2) Essential for animal life. Supports body metabolism (the catabolic breakdown of. A physiologically based pharmacokinetics (PBPK) model for humans, pigs, mice, and rats has been developed to investigate the unique aspects of the chronic administration of inert gas therapies.
Covering new anaesthetics, the molecular and cellular mechanisms of anaesthesia and the non-hypnotic effects of anaesthetics and other medical gases, Gases in Medicine combines reviews of current research from both academic and clinical perspectives and provides an historical framework in which this research may be placed.
Encompassing a wide. This two-volume work of 91 chapters covers all aspects of practice in anaesthesia. Volume 1 addresses the underpinning sciences of anaesthesia including physiology, pharmacology, physics, anaesthetic equipment, statistics, and evidence-based anaesthesia.
Volume 1 also outlines the fundamental principles of anaesthetic practice including ethics, risk, informatics and technology for anaesthesia. nitrogen gas showed that nitrogen has narcotic (= anaesthetic) effects, and this led to the investigation of other chemically inert gases.
The noble – at that time regarded as inert – gases from Group 8 of the periodic table naturally attracted attention, although it was known. Read the latest articles of General Pharmacology: The Vascular System atElsevier’s leading platform of peer-reviewed scholarly literature.
Properties of Inhaled Anesthetics Less potent More potent ANESTHETIC MAC(atm) (oil/gas) (oil/gas) x MAC Nitrous oxide Desflurane 19 Sevoflurane 51 Ether 65 Enflurane 98 Isoflurane 98 Halothane Xenon (Xe) is an inert gas under normobaric conditions.
It has been studied and used as an anesthetic agent. Thus is another popular one form anesthesia gases. It is present in the atmosphere at a concentration of ppm and is a non-pollutant. lt is not metabolized and is not teratogenic.
Stereoselectivily of anaesthetics. Anaesthetic gases represent 5% of the carbon footprint for all acute National Health Service (NHS) organisations, or 50% of gas emissions from the heating of acute NHS buildings and water.7 Likewise, the use of desflurane or sevoflurane from a modern anaesthetic machine for 1 h is the same as or 30 miles travelled in a modern.
The possibility of anaesthesia by the inert gas argon in particular (even at 10 to 15 bar) suggests that the mechanism of action of volatile anaesthetics is an effect best described by physical chemistry, and not a chemical bonding action.
However, the agent may bind to a receptor with a weak interaction. Mode of administration. Drugs given to induce general anaesthesia can be either as gases or vapours (inhalational anaesthetics), or as injections (intravenous anaesthetics or even intramuscular).All of these agents share the property of being quite hydrophobic (i.e., as liquids, they are not freely miscible—or mixable—in water, and as gases they dissolve in oils better than in water).
To descnbe the pharmacokinetic behaviour and practical aspects of low (–1l min−1) and minimal (– l min−1) flow anaesthesia. A Medline search located articles on low flow anaesthesia, and computer simulated anaesthetic uptake models are used. Most, 85–90%, of anaesthetists use high fresh gas flow rates during inhalational anaesthesia.
Low/minimal flow anaesthesia with a.Safety Aspects Introduction. Air Pollution. Ignition in Reboilers. Other Hazards in Air Separation Units. Process Analysis Air Separation Units. Applications of the Air Gases Applications of Nitrogen Applications of Nitrogen for Inerting and Purging.administration of the inert gases Xe and Ar using a physiological based model Ira Katz1,2*, Jacqueline Murdock1, Marc Palgen1, Jan Pype1 and Georges Caillibotte1 Abstract Background: New gas therapies using inert gases such as xenon and argon are being studied, which would require chronically administered repeating doses.